The integrated Bioimaging Facility iBiOs is a core facility within the Center of Cellular Nanoanalytics (CellNanOs), an interdisciplinary Research Center at Osnabrück University. The iBiOs provides access to advanced fluorescence and electron microscopy techniques with highest spatial and temporal resolution. Next to state-of-the-art high-resolution fluorescence imaging techniques, the iBiOs has specialized on live cell single molecule localization microscopy such as PALM/STORM and single molecule tracking as well as single molecule spectroscopy (FLIM, FCS). The iBiOs provides access to cutting-edge techniques such as lattice light-sheet microscopy and develops new nanoparticle based methods such as upconversion microscopy and second harmonic generation microscopy in close collaboration with different research groups at CellNanOs. The EM unit currently applies state-of-the-art 2D scanning and transmission electron microscopy techniques, which are currently extended to 3D and cryo-techniques as well as correlative light-electron microscopy (CLEM). A broad repertoire of labeling techniques is available including the application of nanoparticles in living cells as well as for CLEM for achieving optimum performance.

As a DFG-funded core facility, the iBiOs also provides access to external users. Please, contact us to discuss whether your project can be conducted at our imaging systems.

University of Osnabrück
Center of Cellular Nanoanalytics CellNanOs
Integrated Bioimaging Facility iBiOs
Barbarastr. 11
49076 Osnabrück